Polynucleotide treatment uses purified DNA fragments, often from salmon, injected into the skin to support repair and elasticity. Rejuran is the best-known PN product. It is used for fine lines, thin skin, pores and post-laser healing.
Medically reviewed by [DOCTOR NAME], board-certified dermatologist · Doje Clinic, Apgujeong, Seoul · Last reviewed November 2026
Most patients receive a course of three sessions.
Tell your doctor about any fish allergy.
Quick facts
- Rejuran Healer (PN Skin Booster): Small bumps for 1–2 days; results last around 6–12 months after a full course
Key facts
| Rejuran Healer | Typically 3 sessions 2–4 weeks apart |
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Related treatments
Patient questions
Frequently asked questions
What is polynucleotide (PN) treatment?
Polynucleotide treatment uses purified DNA fragments, often from salmon, injected into the skin to support repair and elasticity. Rejuran is the best-known PN product. It is used for fine lines, thin skin, pores and post-laser healing.
What is Rejuran Healer?
Rejuran Healer is a polynucleotide (PN) skin booster derived from salmon DNA, injected in micro-amounts to improve skin repair, elasticity and texture.
Your skin plan, designed in Apgujeong
English-speaking consultations · Written quotes · Aftercare you can take home
Medical information on this page is general and educational. Results, downtime and suitability vary by individual. A consultation with a Doje Clinic physician is required before any treatment.