Rejuran is an established injectable with clinical use over many years; exosome therapy is newer, usually applied after microneedling, with evidence still developing.
Medically reviewed by [DOCTOR NAME], board-certified dermatologist · Doje Clinic, Apgujeong, Seoul · Last reviewed November 2026
Side by side
| Rejuran Healer | Exosome Skin Therapy | |
|---|---|---|
| Category | Skin Boosters | Skin Boosters |
| Procedure time | 20–40 minutes | 30–45 minutes including microneedling |
| Sessions | Typically 3 sessions 2–4 weeks apart | Often 3–5 sessions |
| Downtime | Small bumps for 1–2 days; possible pinpoint bruising | Redness for 1–2 days |
| Results appear | Gradual over 2–3 sessions | Gradual |
| Results last | Around 6–12 months after a full course | Varies |
| Comfort | Many injection points; numbing cream applied for comfort | Depends on the delivery method |
How Rejuran Healer works
Polynucleotides support the skin's healing environment and fibroblast activity, helping thickness, elasticity and fine texture improve gradually.
How Exosome Skin Therapy works
Exosome products are delivered into micro-channels to support the skin's regenerative environment. Evidence is still emerging and product quality varies.
Choose Rejuran Healer if you have
- thin or damaged skin
- fine lines
- enlarged pores
- post-laser recovery
- sensitive skin
Choose Exosome Skin Therapy if you have
- post-laser recovery
- dull, tired skin
- pairing with microneedling for texture
Can you combine them?
Often, yes — your doctor will decide sequencing and timing based on your skin and travel dates.
Patient questions
Frequently asked questions
Which is better, Rejuran Healer or Exosome Skin Therapy?
Rejuran is an established injectable with clinical use over many years; exosome therapy is newer, usually applied after microneedling, with evidence still developing.
Which has less downtime, Rejuran Healer or Exosome Skin Therapy?
Rejuran Healer: small bumps for 1–2 days; possible pinpoint bruising. Exosome Skin Therapy: redness for 1–2 days.
Which lasts longer?
Rejuran Healer: around 6–12 months after a full course. Exosome Skin Therapy: varies.
Not sure which one is right for you?
A Doje Clinic dermatologist will recommend the option that fits your skin, goals and travel dates.
Medical information on this page is general and educational. Results, downtime and suitability vary by individual. A consultation with a Doje Clinic physician is required before any treatment.